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Other members
1. Prof. Dr. LE Van Thao
2. MSc. PHAM Van Binh
3. MSc. LE Thi Thanh Tuyen
4. BSc. TRAN Phu Duy (PhD. Stud.)
5. MSc. PHAM Xuan Thanh Tung
Introduction
Nanobiosensors group develops and produces various nanostructures for sensor technology, including nanowires of various materials, single nanopore membrane, nanoelectrodes, nanogaps, nanoresonators and nanocantilevers etc. All these structures with the dimensions of the active part down to a few nanometers can be used to build up many kinds of smart and powerful nanosensors as reported recently by researchers around the world. Especially, we develop a new fabrication process that utilizes only techniques of conventional microfabrcation technology to fabricate an array of nanowires of various materials at a wafer-scale. In addition, each nanowires from the fabricated array is individually electrically addressed, thus making easily to be connected to outer electronics control for further characterization as well as building up interested nanowire based nanodevices.
Currently, in the frame of the National Key Project (KC.04.12/06-10,) research of the Nanobiosensors has been devoted to made then apply the fabricated nanowires ( Pt and Si) as biosensors for detection of several important biological species like glucose, ADNs, and Proteins. Applications for the developed sensors are ranging in various vital sectors like healthcare, food industry, and environment etc.
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Conducted Projects
1. Study on fabrication technology of DNA chip used in biology analysis
2. Study on application MEMS technology for fabricating micro array used in biology analysis
3. Study on fabricating platinum nanowire used for diagnosing glucose’s quantity in blood
3. Study on the immobilization of glucose oxidase enzyme on platinum nanowire for detecting glucose
4. Study on quantitative analysis glucose using platinum thin film
5. Study on fabrication of nano bio-sensor for diagnosis and quantitative analysis of some biological compounds
6. Study on fabrication of nano bio-sensor for diagnosis and quantitative analysis of some biological compounds
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Publications
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Pham Xuan Thanh Tung, Le Thi Thanh Tuyen, Tran Phu Duy, Pham Van Binh, Tong Duy Hien and Dang Mau Chien 2010, Oxidation of platinum microwires surface applied in glucose detection, Adv. Nat. Sci: Nanosci. Nanotechnol. 1 025013
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Tong Duy Hien, Tran Phu Duy, Pham Xuan Thanh Tung, Pham Van Binh, Le Thi Thanh Tuyen, Dang Mau Chien and Cees J M Van Rjin 2010 Nanofabrication of Pt nanowire arays at wafer-scale and its application in glucose detection, Adv. Nat. Sci: Nanosci. Nanotechnol. 1 015011
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Thi Thanh Tuyen Le, Phu Duy Tran, Xuan Tung Pham, Duy Hien Tong and Mau Chien Dang 2010 Glucose oxidase immobilization on different modified surfaces of platinum nanowire for an application in the glucose detection, Advances In Natural Sciences: Nanoscience And Nanotechnology 1 55-60
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Le Thi Thanh Tuyen, Tran phu Duy, Pham Xuan Tung, Tong Duy Hien and Dang Mau Chien 2009 Glucose oxidase immobilization on different modified surfaces of platinum nanowire for an application in the glucose detection, Proceedings of IWNA 2009 (Vung Tau, Vietnam, 12-14 November 2009) pp 604-607
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Pham Xuan Thanh Tung, Le Thi Thanh Tuyen, Tran Phu Duy, Tong Duy Hien and Dang Mau Chien 2009 Oxidation of platinum microwires surface and its application in glucose detection, Proceedings of IWNA 2009 (Vung Tau, Vietnam, 12-14 November 2009) pp 608-612
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Tong Duy Hien, Pham Xuan Thanh Tung, Tran Phu Duy, Pham Binh, Le Thanh Tuyen , Cees J.M. van Rijn, Dang Mau Chien 2009 Nanofabrication of ready for measurement Pt nanowires at a wafer-scale and its application in glucose detection, Proceedings of IWNA 2009 (Vung Tau, Vietnam, 12-14 November 2009) pp 69-73
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Tran Nhan Ai, Le Thi Thanh Tuyen, Dang Le Khoa, Tong Duy Hien and Dang Mau Chien 2009 Glucose sensing of sputtered Pt electrodes, Advances in Natural Sciences 10 45-50
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Hien Duy Tong et al 2009 Novel Top-Down Wafer-scale fabrication of Single Crystal Silicon Nanowires, Nanoletter 9 1015-1022
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Javier Tomayor, Hien Duy Tong et al 2009 Array of dual nanomechanical resonators for selectice biological detection Anal. Chem. 81 2274-2279
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P. Offermans, Hien Duy Tong, C.J.M Van Rijn, P. Merken, S.H Brongersma and M. Cregocalama 2009 Ultra-low power hydrogen sensing with single palladium nanowires, Applied Physics Letter 94 223
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V.J. Gadgil, Hien Duy Tong and Y. Cesa, M.L. Bennik 2009 Fabrication of nano structures in thin membranes with focused ion beam technology, Surface and Coating Technology 203 2436-2441
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Nguyen Hoang Phuong Uyen, Mai Thi Anh Dao, Tong Duy Hien, Dang Mau Chien 2007 Investigation of immobilization process of ligonucleotide on microfabricate microarrays Proceedings of IWNA 2007 (Vung Tau, Vietnam, 15-17 November 2007) pp 580-583
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Tran Nhan Ai, Nguyen Dang Khoa, Le Thi Thanh Tuyen, Tong Duy Hien and Dang Mau Chien 2007 Study on glucose sensing of sputtered Pt electrodes Proceedings of IWNA 2007 (Vung Tau, Vietnam, 15-17 November 2007) pp 576-579
Collaboration Information
1. Nanosens Research B.V , The Netherlands
2. MESA+ Research Institutes for Nanotechnology, The Netherlands
3. Wageningen University, The Netherlands
4. Institutes of Agricultural Genetic, Vietnam
5. Institute of Tropical Biotechnology, Vietnam
6. Cho Ray Hospital, Vietnam.
Technology transfer
Several batches of our fabricated nanowire chips have been made and transferred for our research partners at hospitals and biological research institutes for further application in detections of glucose, ADNs, and proteins, and viruses etc. Beside biological section, which is given our highest priority at this moment, we will soon fabricate nanowire chips of appropriate materials for other applications in various sectors like nanoelectronics, nanomagnetics, and optics etc.
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Contact Information
MSc. LE Thi Thanh Tuyen
Phone: +84 08 3 7242160 (ext 4632) - Fax: +84 08 3 7242163
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028 37 2468 23 /32
